Daufuskie Island Vacation Rentals
Staying on the Island
From family vacations, to romantic getaways, girls’ weekends, and golf outings with the guys, Daufuskie Island has accommodations to suit your agenda—or deliberate lack thereof.
Melrose on the Beach
Discover a selection of 53 vacation rentals in Melrose on the Beach, Daufuskie Island that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $258 per night, and cottages and houses are popular options for a stay in Melrose on the Beach.